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Protein pull down assay is an in vitro affinity purification method that uses a bait protein to enrich proteins that interact with the bait protein. It can be used for confirmation of existing protein-protein interactions discovered by other techniques or initial screening to identify novel protein-protein interactions. Profacgen provides you protein pull down service for the detection of possible interacting proteins of your target proteins.
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The interactions between proteins and peptides play essential functional roles in living organisms and they can be found in a variety of signaling pathways involved in cellular localization, immune response or protein expression and degradation. Erroneous protein-peptide interactions are associated with a number of diseases (e.g., cancer, autoimmune diseases). The understanding of protein-peptide interactions is critical for targeted drug design and their structural characterization is a hot subject of current experimental and theoretical research.